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Ph.D., University of British Columbia
Postdoctoral Research Associate
Gramene Project (www.GRAMENE.org)
Contact information:
Department of Plant Breeding and Genetics
259 Emerson Hall, Cornell University
Ithaca, New York, 14850 U.S.A.
Email:
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Tel: 1-607-255-2089
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Research focus:
My research interest has two major components that both are associated with the core of understanding the complexity of biotic
and abiotic forces that shape natural biodiversity.
FIRST, uncovering how the factors, genetic, ecological and evolutionary, that defines the patterns and dynamics of observed
standing diversity.
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Motivated by phylogenetic analyses, I take on the traditional
quantitative genetic approaches and generate the first lineage
specific QTL map in floral trait evolution of three Mimulus species.
Selected reference:
Charles Chen and Kermit Ritland. Lineage specific inference about
quantitative trait locus evolution among three taxa of the yellow
monkey flower species complex. Heredity 2011.
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SECOND, the ability to take advantages of the explosion of genomic data
will depend on whether these data can be fully integrated into an evolutionary
and biological context.
Affiliated with a comparative plant genomic database, www.GRAMENE.org,
I am working on implementing a computational approach that incorporate
multiple layer of evidences, such as GWAS associations, gene annotations
and orthologous relationships, to systematically characterize the functional
candidates that govern genetic architecture of complex traits like flowering
time variation in crop species.
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Selected reference:
Youens-Clark, K., Buckler, E., Casstevens, T., Chen, Charles, Declerck G., Derwent P., Dharmawardhana P., Jaiswal P. Kersey P., Karthikeyan AS., Lu J.,
McCouch SR., Ren L., Spooner W., Stein JC., Thomason J., Wei S., Ware D. Gramene Database in 2010, updates and extensions. Nucleic Acids Research
2010. PMID:21076153
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